Can you iv morphine sulfate

Prevalence of opioid analgesic injection among rural opioid analgesic users. Drug Alcohol Depend. Article Google Scholar. Surveillance des maladies infectieuses chez les utilisateurs de drogue par injection. Paulozzi LJ. Opioid analgesic involvement in drug abuse deaths in American metropolitan areas. Am J Public Health.

Prescription opioid abuse among enrollees into methadone maintenance treatment. The Royal Australasian College of Physicians, Prescription Opioid Policy: improving management of chronic non-malignant pain and prevention of problems associated with prescription opioid use, Sydney; Route of administration for illicit prescription opioids: A comparison of rural and urban drug users. Harm Reduct J. The health consequences of injecting tablet preparations: foreign body pulmonary embolization and pulmonary hypertension among deceased injecting drug users.

Del Giudice P. Cutaneous complications of intravenous drug abuse. Br J Dermatol. Pulmonary talc granulomatosis. A complication of drug abuse. Am Rev Respir Dis. Long-term follow-up of drug abusers with intravenous talcosis. Injection of pharmaceuticals designed for oral use: harms experienced and effective harm reduction through filtration. Curr Top Behav Neurosci. Reducing harm from injecting pharmaceutical tablet or capsule material by injecting drug users.

Drug and Alcohol Rev. Scott J. Safety, risks and outcomes from the use of injecting paraphernalia. Edinburgh, U. Scottish Executive; Tendances OFDT; Keijzer L, Imbert I. The filter of choice: filtration method preference among injecting drug users. Uptake of wheel-filtration among clients of a supervised injecting facility: can structured education work?

Drug Alcohol Rev. Edited by Apothicom www. Method for increasing the solubility of morphine and pharmaceutical compositions prepared therefrom. Effect of filtration on morphine and particle content of injections prepared from slow-release oral morphine tablets. Vermeire A, Remon JP.

The solubility of morphine and the stability of concentrated morphine solutions in glass, polypropylene syringes and PVC containers. Int J Pharm. Dosage des seringues de « shoot » de sulfate de morphine. Recovering infectious HIV from novel syringe-needle combinations with low dead space volumes. Survival of hepatitis C virus in syringes is dependent on the design of the syringe-needle and dead space volume.

PLoS One. Download references. The Fund would like to thank the people who inject drugs for raising these questions but also for finding methods that reduce, as this study shows, harm associated to the injection of this pharmaceutical.

We would also like to thank Ethypharm for accepting to perform the lab work to support this study. This study was funded by Apothicom Distribution, that is, Apothicom Distribution paid for the lab work done by Ethypharm. You can also search for this author in PubMed Google Scholar.

LK proposed the protocol. Ethypharm provided the morphine sulphate and did the lab work. LK wrote the article, based on the report provided by Ethypharm. The author read and approved the final manuscript. Correspondence to Lenneke Keijzer. FRPA is a philanthropic organisation whose main mission is to reduce health risks resulting from drug use, in particular in people who inject drugs, a mission completely in line with the scope of this article.

Indirectly, the financial situation of Apothicom Distribution thus has an influence on the financial health of the research and prevention fund. The author thus has a professional and a personal interest in difficulties encountered by PWID when filtering their drugs, as well in filters as harm reduction tools.

She has received no fee from Apothicom Distribution for this work, nor does she have any stock options of this company. From my point of view, this type of studies on the efficacy and studies on the acceptability by PWID of harm reduction methods and tools are an important part of our work and help us to provide a service of a better quality. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. Reprints and Permissions. Keijzer, L. Reducing harm through the development of good preparation practices for the injection of slow release morphine sulphate capsules.

Harm Reduct J 17, 48 Download citation. Received : 19 June Accepted : 10 June Published : 16 July Anyone you share the following link with will be able to read this content:. Sorry, a shareable link is not currently available for this article. Provided by the Springer Nature SharedIt content-sharing initiative. Skip to main content. Search all BMC articles Search. Download PDF. Abstract Background It is not always easy to advise people who inject drugs PWID on how to prepare their drugs in a way that is associated with reduced harm.

Conclusions The provision of a method that is easy to use, reduces harms associated to the injection of insoluble particles and recovers virtually all the active drug has a large chance to be adopted by people who use drugs. Objective This study was set up to examine the influence of different preparation practices, including filtration, on particle count, morphine concentration and filtration ease.

Our hypothesis is that more morphine is extracted in a 2-mL solution after heating. Though the majority use this method, other preparation methods are used. Full size image. Methods Two preparation practices are thoroughly explored. Protocol for the cold preparation technique A mg morphine sulphate capsule was opened, and the microbeads were put on a carefully folded piece of paper. Three additional tests were performed: Rinsing of wheel filters : It is known that wheel filters have a high void volume and retain part of the solution [ 12 , 14 ].

The three membrane filters were used alone, a combined filtration was not necessary. Data collection Three tests were performed per preparation technique. Particle retention Without filtration, a large number of insoluble particles are observed in the morphine sulphate solution, consisting of starch and talc particles. Comparison of the cold and lukewarm preparation techniques, according to the filter used Full size table.

Conclusions When slow release morphine sulphate capsules are diverted by injection, the use of filters is essential to prevent long term complications due to the injection of insoluble drug fillers such as talc and starch. Availability of data and materials Additional data and figures that support the findings of this study are available. References 1. Article Google Scholar 3. Article Google Scholar 5.

Article Google Scholar 6. Article Google Scholar 8. Article Google Scholar 9. Article Google Scholar Acknowledgements The Fund would like to thank the people who inject drugs for raising these questions but also for finding methods that reduce, as this study shows, harm associated to the injection of this pharmaceutical. Funding This study was funded by Apothicom Distribution, that is, Apothicom Distribution paid for the lab work done by Ethypharm.

About this article. Cite this article Keijzer, L. Copy to clipboard. Use morphine injection at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Your doctor may adjust your dose of morphine injection during your treatment, depending on how well your pain is controlled and on the side effects that you experience. Talk to your doctor about how you are feeling during your treatment with morphine injection.

If you have used morphine injection for longer than a few days, do not stop using it suddenly. If you suddenly stop using morphine injection, you may experience withdrawal symptoms including restlessness; teary eyes; runny nose; yawning; sweating; chills; muscle, back or joint pain; widening of the pupils; irritability; anxiety; weakness; stomach cramps; difficulty falling asleep or staying asleep; nausea; loss of appetite; vomiting; diarrhea; fast breathing; or fast heartbeat.

Your doctor will probably decrease your dose gradually. This medication may be prescribed for other uses; ask your doctor or pharmacist for more information. Morphine may cause other side effects. Call your doctor if you have any unusual problems while you are using this medication. In case of overdose, call the poison control helpline at If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at While using morphine injection, you should talk to your doctor about having a rescue medication called naloxone readily available e.

Naloxone is used to reverse the life-threatening effects of an overdose. It works by blocking the effects of opiates to relieve dangerous symptoms caused by high levels of opiates in the blood.

Your doctor may also prescribe you naloxone if you are living in a household where there are small children or someone who has abused street or prescription drugs.

You should make sure that you and your family members, caregivers, or the people who spend time with you know how to recognize an overdose, how to use naloxone, and what to do until emergency medical help arrives.

Your doctor or pharmacist will show you and your family members how to use the medication. Ask your pharmacist for the instructions or visit the manufacturer's website to get the instructions.

If symptoms of an overdose occur, a friend or family member should give the first dose of naloxone, call immediately, and stay with you and watch you closely until emergency medical help arrives. Your symptoms may return within a few minutes after you receive naloxone. If your symptoms return, the person should give you another dose of naloxone.

Additional doses may be given every 2 to 3 minutes, if symptoms return before medical help arrives. Keep all appointments with your doctor and laboratory. Your doctor may order certain lab tests to check your body's response to morphine.

Before having any laboratory test especially those that involve methylene blue , tell your doctor and the laboratory personnel that you are using morphine. This prescription is not refillable.

If you are using morphine to control your pain on a long term basis, be sure to schedule appointments with your doctor so that you do not run out of medication. If you are using morphine on a short-term basis, call your doctor if you continue to experience pain after you finish the medication.

It is important for you to keep a written list of all of the prescription and nonprescription over-the-counter medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies. Morphine Injection pronounced as mor' feen. Why is this medication prescribed?

How should this medicine be used? Other uses for this medicine What special precautions should I follow? What special dietary instructions should I follow? What side effects can this medication cause? Brand names. Talk to your doctor about the risks of using morphine injection. Other uses for this medicine.

What special precautions should I follow? Before using morphine injection, tell your doctor and pharmacist if you are allergic to morphine, any other medications, or ingredients in morphine injection. Ask your pharmacist for a list of the ingredients. Also tell your doctor or pharmacist if you are taking or receiving the following monoamine oxidase MAO inhibitors or if you have stopped taking them within the past two weeks: isocarboxazid Marplan , linezolid Zyvox , methylene blue, phenelzine Nardil , selegiline Eldepryl, Emsam, Zelapar , or tranylcypromine Parnate.