Which chromosome contains sex linked genes
The X chromosome contains multiple immune-related genes and immune regulatory elements as well as the XIC that regulates X chromosome inactivation. It is therefore clear that the X chromosome is involved in the immune response and genes that escape inactivation or are preferentially inactivated could influence the dosage of X-linked gene expression between the sexes and as such could further influence the sex bias in disease.
It is thus of vital importance that the XCI mechanisms be further investigated to understand all the regulatory elements involved and the contribution to sex bias. Furthermore, the role of the X chromosome in the innate and adaptive immune response should be extensively investigated to determine how it contributes and differs between the sexes. Elucidating the function of the X chromosome and including it in biological studies and analyses could improve the understanding of complex diseases such as TB.
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Men normally have an X and a Y combination of sex chromosomes, while women have two X's. Since only men inherit Y chromosomes, they are the only ones to inherit Y-linked traits. Men and women can get the X-linked ones since both inherit X chromosomes. Sex cell inheritance patterns for male and female children X-linked recessive traits that are not related to feminine body characteristics are primarily expressed in the observable characteristics, or phenotype , of men.
This is due to the fact that men only have one X chromosome. Subsequently, genes on that chromosome not coding for gender are usually expressed in the male phenotype even if they are recessive since there are no corresponding genes on the Y chromosome in most cases. In women, a recessive allele on one X chromosome is often masked in their phenotype by a dominant normal allele on the other. This explains why women are frequently carriers of X-linked traits but more rarely have them expressed in their own phenotypes.
The "a" r ecessive allele will be expressed in his phenotype The "a" recessive allele will not be expressed in her phenotype male female There are about 1, human X-linked genes. Most of them code for something other than female anatomical traits.
Many of the non-sex determining X-linked genes are responsible for abnormal conditions such as hemophilia , Duchenne muscular dystrophy , fragile-X syndrome , some high blood pressure, congenital night blindness, G6PD deficiency, and the most common human genetic disorder, red-green color blindness.
X-linked genes are also responsible for a common form of baldness referred to as "male pattern baldness". Cell Division 2: Molecular Biology 1. Metabolic Molecules 2. Water 3. Protein 5. Enzymes 6. Cell Respiration 9. Photosynthesis 3: Genetics 1. Genes 2. Chromosomes 3. Meiosis 4. Inheritance 5. Genetic Modification 4: Ecology 1. Energy Flow 3. Carbon Cycling 4.
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